What significant events occurred during the 400 years of silence in history"?

During the 400 years of silence in history, significant events included the rise of the Greek Empire, the conquests of Alexander the great, the spread of Hellenistic culture, and the eventual conquest of the region by the Roman Empire. This period also saw the translation of the Hebrew Bible into Greek, known as the Septuagint, and the emergence of various Jewish sects such as the Pharisees, Sadducees, and Essenes.