Can you take a bus to go from Charlotte to Myrtle Beach. And if so which one?

Yes you can. On Greyhound. A Greyhound bus ticket from Charlotte to Myrtle Beach will cost approximately $77.44 - $99.00 depending on the fare type selected. The price of a bus ticket depends on the fare type purchased (example: refundable, non-refundable, return, one-way). Price confirmation can be obtained online or through your local Greyhound Operator.