In the 1500s the new woprld was dominated by who?

In the 1500s, the New World was primarily dominated by European powers, particularly Spain and Portugal, following the Age of Exploration. Spanish conquistadors like Hernán Cortés and Francisco Pizarro established control over large territories in the Americas, including the Aztec and Inca empires. Portugal focused on Brazil and established trade routes. This period marked the beginning of European colonialism, significantly impacting indigenous populations and cultures.