How do antiepileptic drugs affect the skin?

Certain antiepileptic drugs (AEDs) do affect the skin. For example, some people on carbamazepine (Tegretol) develop skin rashes with excessive sun exposure. With regard to lamotrigine (Lamictal), a very small percentage of individuals develop a rash (usually within the first week of use) that can be serious if the medication is not immediately discontinued (e.g. Stevens-Johnson Syndrome). There are others that can affect the skin, as well.