How does Goitre Iodine deficiency affect the body?

The thyroid gland produces thyroxine and triiodothyronine which essential element is iodine. It order for these hormones to function they need iodine. Without these hormones the thyroid can not function properly and swells (goiter). Reduced function in the thyroid also caused the hypothalamus and pituitary gland to produce thyroid stimulating hormone which irritates the thyroid more.