When animal blood is mixed with physiologic saline, the saline solution helps to maintain the osmotic balance and provides a suitable environment for the cells. Red blood cells may remain intact if the saline is isotonic, but if the saline is hypotonic, it can cause the cells to swell and potentially burst due to osmotic pressure. Additionally, the saline can dilute the blood components, affecting its viscosity and the concentration of cells and proteins. Overall, the interaction depends on the saline's tonicity relative to the blood.
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