Can the Bill of Rights be subject to interpretation by the US Supreme Court?

Yes, by the same process that amendments to the Constitution itself are made. Article 5 provides for amending the Constitution. Since the Constitution itself can be amended and since the Bill of Rights is a part of the Constitution, then it can be amended as well. The Bill of Rights is just a name given to the first ten amendments. They have no special status. The 18th amendment, Prohibition, was itself amended out of existence by the 21st amendment.