It depends on the length of time and time of year.
Snakes have a natural cycle of estivation, which is similar to hibernation, so their appetite changes.
Also certain snakes will only eat living, moving or warm animals so try to feed it different types of rodents. I used to feed a snake at the zoo who loved eating baby mice and refused to eat dwarf hamsters, so we had to special order the mice for him and he began to eat again.
*If you are truly worried then take it to a vet
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