Can AA can marry AS

Yes, an AA individual can marry an AS individual, but there is a risk of having offspring with sickle cell disease (SS). In this pairing, there is a 25% chance that their children could inherit the sickle cell trait (AS), a 50% chance of being carriers (AS), and a 25% chance of having sickle cell disease (SS). Couples in this situation may want to consider genetic counseling to understand their options and the implications for their future children.