This is a question that you should ask your pharmacist or physician.
The pharmacist says it depends - if you are legally prescribed Adderall and have a cold or runny nose, go ahead - just follow the directions and do not take more of either drug than it says to.
If you are trying to get high, you have no idea what effect taking drugs will have - people who are legally prescribed drugs have been examined by a doctor, who takes their medical history to be sure it's safe for them to take - and even then, you get side effects, sometimes very serious ones! Taking drugs illegally is just dumb.
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