RST is an abbreviation with multiple meanings, including:
- RST code (readability, strength, tone), used to record the quality of radio signals
- IATA airport code for Rochester International Airport in Rochester, Minnesota
- Stock ticker symbol for Rosetta Stone_(software)
- RsT, a compiled hex used on Funcards to allow theft of Cable Television
- Registered Safe Technician, as awarded by the National Safeman's Organization
- Reset flag in the Transmission Control Protocol (TCP)
- reStructuredText, a lightweight markup language which uses the file extension .rst
- Retail sales tax, common sales tax
- The Royal Shakespeare Theatre, a theatre at Stratford-upon-Avon in the United Kingdom
- Reverse Semantic Traceability - the software quality control method
- Regularly scheduled training
- Reservoir Saturation Tool, a logging term used in the Oil and Gas industry.
- Rytų skirstomieji tinklai - An electricity supply corporation in Eastern Lithuania.
- Red Stars Theory - a rock band from Seattle, Washington.
- ReSeT or ReStarT
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