A cell may have a different type of receptor that can only bind to one chemical messenger. The effect of the chemical messenger on the cell is dependent on the type of receptor that it binds to. For example, acetylcholine can bind to a nicotinic cholinergic receptor on a neuromuscular junction and cause an excitatory response, but acetylcholine can also bind to a muscarinic cholinergic receptor on the heart's cardiac muscle which can be either excitatory/inhibitory.
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